Who are the Global PrAKI Consortium?
We are an active group of international researchers, clinicians, educators, policy makers, and organisations aiming to improve the prediction, prevention, identification and management of PrAKI.
Members contribute to research, education, or advocacy activities.
The Global PrAKI Academy is the educational arm of the Consortium, focused on knowledge dissemination and capacity building.
The Consortium is part of CRIBS International.
Why does PrAKI matter?
PrAKI is a leading cause of maternal morbidity & mortality globally
•PrAKI significantly increases the risk of maternal death, particularly in low- and middle-income countries
•In some settings, maternal mortality rates in women with PrAKI can be as high as 37%, especially when critical care and dialysis are unavailable
PrAKI is underdiagnosed, under-recognised & often avoidable
•Early stages of PrAKI are often missed due to nonspecific symptoms & physiological changes in pregnancy that mask kidney dysfunction.
•Routine pregnancy care often lacks proactive renal monitoring, especially in women with preeclampsia, haemorrhage or sepsis, key contributors to PrAKI.
Hypertensive disorders of pregnancy are a major precursor
•Conditions like preeclampsia and HELLP syndrome are among the most common causes of PrAKI.
•These hypertensive disorders can lead to multi-organ dysfunction directly impacting kidney blood flow.
Even mild PrAKI has long-term consequences
•Women who survive PrAKI have a significantly higher risk of developing chronic kidney disease (CKD) & cardiovascular disease later in life.
•This risk persists even if creatinine levels (a marker of kidney function) return to baseline postpartum, highlighting the need for long-term follow-up.
PrAKI disproportionately affects vulnerable populations
•Social determinants, such as poor access to antenatal care & systemic inequities, increase incidence and severity of PrAKI in marginalised groups.
•Racial and ethnic disparities remain stark: Black and Asian women are at higher risk of both hypertensive disorders and kidney complications.
Founders and Leads
-
-
Maternal Medicine & Nephrology Lead and Founder
Reader of Nephrology and Maternal Medicine at King’s College London, UK
Honorary Consultant Nephrologist
-
-
Founding Members
Contact us
Interested in working together? Fill out some info and we will be in touch shortly. We can’t wait to hear from you!